Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, ... show all 50 brands Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Citracal + D, Oystercal-D, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Caltrate 600+D Soft Chews, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, UpCal D, Os-Cal Extra D3, D3 with Calcium, Calcium Plus Vitamin D3
Dosage forms: oral capsule (600 mg-10 mcg; 600 mg-12.5 mcg; 600 mg-5 mcg; 600 mg-62.5 mcg), oral liquid (1000 mg-10 mcg/30 mL), ... show all 16 dosage forms oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)
Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on Jun 17, 2025. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Less serious side effects may be more likely, or you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Follow all directions on the label and package. Use exactly as directed. Tell your healthcare provider if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use calcium and vitamin D combination if you are allergic to it.

Ask a doctor or pharmacist before using calcium and vitamin D combination if you have health problems or use other medications.

Ask a doctor before using calcium and vitamin D combination if you plan to become pregnant, are pregnant, or are breastfeeding. Your dose needs may be different during pregnancy or while you are nursing.

Do not give any herbal/health supplement to a child without medical advice.

How should I take calcium and vitamin D combination?

If you choose to use calcium and vitamin D combination, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Your dose needs may change if you switch to a different brand, strength, or form of calcium and vitamin D combination. Avoid medication errors by using exactly as directed on the label, or as prescribed by your doctor.

Taking more than your recommended dose will not make calcium and vitamin D combination product more effective, and may cause serious side effects.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Shake the oral liquid. Measure a dose with the supplied measuring device (not a kitchen spoon).

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your dose may need to be adjusted as you make changes to your diet. Follow your doctor's instructions very closely.

The recommended daily dose of calcium and vitamin D changes with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the NIH, or the USDA Nutrient Database of recommended daily allowances for more information.

Follow all storage instructions provided with calcium and vitamin D combination. Your pharmacist can provide more information about how to store calcium and vitamin D combination.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium - General Range: 1000 mg to 1300 mg daily

Vitamin D - General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium - General Range: 1000 mg to 1300 mg daily

Vitamin D - General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

What happens if I miss a dose?

Take calcium and vitamin D combination as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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